Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 6/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24042813 | 0.80 | SYK (0.40) | MAPK9SYK | |
| SCHEMBL2852000 | 0.77 | KDM4E (0.44) | MAPK10MAPK8SYKHTR1A | |
| SCHEMBL22256859 | 0.77 | SYK (0.37) | MAPK9MAPK10MAPK8SYKHTR1A | |
| SCHEMBL10249073 | 0.73 | HRH4 (0.43) | HRH4PIM1PIM2PIM3 | |
| SCHEMBL1554844 | 0.72 | RAB9A (0.52) | SYK | |
| SCHEMBL17700440 | 0.72 | CHRNA7 (0.53) | HRH4 | |
| SCHEMBL91488 | 0.72 | HRH4 (0.50) | MAPK9MAPK10HRH4MAPK8ABL1 | |
| SCHEMBL2844731 | 0.72 | ABL1 (0.52) | MAPK9MAPK10HRH4MAPK8PIM1 | |
| SCHEMBL14871556 | 0.71 | CDK2 (0.57) | SYKPIM1ABL1 | |
| SCHEMBL27109892 | 0.71 | CTSK (0.59) | MAPK9MAPK10HRH4MAPK8PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220079928-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONIST AND PREPARATION METHOD THEREFOR | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2022-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220079928-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONIST AND PREPARATION METHOD THEREFOR | LPAR1, LPAR2, LPAR4 | MAPK9 1342/4885MAPK10 641/4885HRH4 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.