SCHEMBL22257500

SCHEMBL22257500

Cc1cc(-c2ccccc2S(=O)(=O)O)c2ccc3c(-c4ccccc4S(=O)(=O)O)cc(C)nc3c2n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.37
MAPT P10636 4/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
APEX1 P27695 1/20 0.37
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
RCE1 Q9Y256 1/20 0.35
PGAM1 P18669 1/20 0.35
SNCA P37840 2/20 0.35
HCRTR1 O43613 1/20 0.34
HCRTR2 O43614 1/20 0.34
MAOB P27338 1/20 0.34
HTT P42858 2/20 0.34
CHAT P28329 1/20 0.34
TNNI3 P19429 1/20 0.34
TNNT2 P45379 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10372240 0.79 MMP2 (0.41) MAPTKDM4ERCE1SNCACHAT
SCHEMBL29625838 0.79 MMP2 (0.41) MAPTKDM4ERCE1SNCACHAT
SCHEMBL10334282 0.78 MMP2 (0.41) MAPTKDM4ERCE1SNCACHAT
SCHEMBL10334285 0.78 MMP2 (0.41) MAPTKMT2AMEN1KDM4ERCE1
SCHEMBL10372590 0.76 RCE1 (0.34) MAPTAPEX1KDM4EL3MBTL1RCE1
SCHEMBL458284 0.74 SMN1; SMN2 (0.48) MYCMAPTKMT2AMEN1KDM4E
SCHEMBL29674811 0.74 ALDH1A1 (0.43) MAPTKMT2AMEN1APEX1KDM4E
SCHEMBL31240983 0.74 ALDH1A1 (0.43) MAPTKMT2AMEN1APEX1KDM4E
SCHEMBL17612640 0.74 ALDH1A1 (0.43) MAPTKMT2AMEN1APEX1KDM4E
Bathocuproine SCHEMBL4393344 0.74 CRHR1 (0.39) MAPTKDM4EHSD17B10HPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200232993-A1 METHODS AND COMPOSITIONS FOR FLUORESCENT AND COLORIMETRIC PROTEIN QUANTITATION PIERCE BIOTECHNOLOGY, INC. 2020-07-23 US disclosed