Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22258549 | 0.94 | LTA4H (0.47) | LTA4HSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL22258560 | 0.86 | RAB9A (0.42) | ALDH1A1SMN1; SMN2MAPTCYP1A2CYP2D6 | |
| SCHEMBL22235674 | 0.86 | KDR (0.51) | LTA4HSMN1; SMN2L3MBTL1MAPTNPSR1 | |
| SCHEMBL22258490 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2CYP1A2KDRCYP2C19 | |
| SCHEMBL22258496 | 0.84 | CYP11B1 (0.36) | ALDH1A1SMN1; SMN2MAPTCYP1A2NPSR1 | |
| SCHEMBL22258534 | 0.81 | LMNA (0.40) | ALDH1A1MAPTKDM4E | |
| SCHEMBL22258448 | 0.81 | LMNA (0.46) | ALDH1A1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL22236099 | 0.80 | NAMPT (0.53) | LTA4HMAPTNPSR1KDM4EMEN1 | |
| SCHEMBL22258542 | 0.78 | NPC1 (0.42) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL22258818 | 0.77 | HTT (0.43) | MAPTNPSR1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |