Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 6/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22235858 | 0.88 | NAMPT (0.46) | NAMPTTRPV1GAAKDM4EALDH1A1 | |
| SCHEMBL22258549 | 0.87 | LTA4H (0.47) | RAB9ANAMPTNPC1KDM4ELMNA | |
| SCHEMBL22258552 | 0.86 | LTA4H (0.48) | CYP1A2CYP2C19CYP2D6KDM4EALDH1A1 | |
| SCHEMBL22258490 | 0.83 | SMN1; SMN2 (0.40) | RAB9AGAACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL22258496 | 0.80 | CYP11B1 (0.36) | RAB9AGAACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL22258534 | 0.77 | LMNA (0.40) | RAB9ANAMPTGAANPC1KDM4E | |
| SCHEMBL16668814 | 0.76 | RAB9A (0.69) | RAB9ANAMPTGAACYP1A2CYP3A4 | |
| SCHEMBL30299173 | 0.76 | RAB9A (0.69) | RAB9ANAMPTGAACYP1A2CYP3A4 | |
| SCHEMBL22258448 | 0.74 | LMNA (0.46) | RAB9ANAMPTNPC1ALDH1A1LMNA | |
| SCHEMBL22236099 | 0.74 | NAMPT (0.53) | RAB9ANAMPTGAANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |