Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | BCL6 | P41182 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22258552 | 0.94 | LTA4H (0.48) | LTA4HKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22258560 | 0.87 | RAB9A (0.42) | NAMPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL22236099 | 0.86 | NAMPT (0.53) | LTA4HNOTUMNAMPTKDM4EKDM6B | |
| SCHEMBL22258490 | 0.85 | SMN1; SMN2 (0.40) | NOTUMRAB9ASMN1; SMN2CYP19A1 | |
| SCHEMBL22258496 | 0.83 | CYP11B1 (0.36) | KDM4ERAB9ASMN1; SMN2CYP19A1NPC1 | |
| SCHEMBL22258491 | 0.83 | RAB9A (0.37) | NAMPTKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL22258475 | 0.81 | NPC1 (0.49) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22235674 | 0.80 | KDR (0.51) | LTA4HNAMPTSMN1; SMN2LMNASGMS2 | |
| SCHEMBL22258448 | 0.80 | LMNA (0.46) | NOTUMNAMPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL22258534 | 0.80 | LMNA (0.40) | NOTUMNAMPTKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |