SCHEMBL2226259

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17448503	0.80	NQO1 (0.50)	NQO1CA1CA2CA7CA9
	SCHEMBL5950717	0.79	CA1 (0.46)	CA1CA2CA7CA9CA12
	SCHEMBL28016714	0.79	CA2 (0.47)	NQO1CA1CA2CA7CA9
	SCHEMBL357145	0.78	CA1 (0.61)	NQO1CA1CA2CA7CA9
	SCHEMBL31116611	0.78	CA1 (0.61)	NQO1CA1CA2CA7CA9
	SCHEMBL30952013	0.78	NQO1 (0.48)	NQO1CA1CA2CA7CA9
	SCHEMBL1501174	0.76	CA1 (0.58)	CA1CA2CA7CA9CA12
	SCHEMBL5759879	0.76	IDO1 (0.47)	NQO1CA1CA2CA7CA9
	SCHEMBL3179355	0.75	NQO1 (0.67)	NQO1CA1CA2CA7CA9
	SCHEMBL17447192	0.75	HDAC4 (0.46)	NQO1CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.