SCHEMBL3179355

SCHEMBL3179355

COc1ccc(OC)c2cc3c(OC)ccc(OC)c3cc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.67
CA2 P00918 4/20 0.50
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
ACHE P22303 1/20 0.50
IDO1 P14902 1/20 0.48
CA4 P22748 2/20 0.47
EP300 Q09472 1/20 0.46
KAT8 Q9H7Z6 1/20 0.46
ALDH1A1 P00352 3/20 0.44
CYP3A4 P08684 3/20 0.44
IMPDH2 P12268 1/20 0.43
IMPDH1 P20839 1/20 0.43
TSHR P16473 3/20 0.42
MAPT P10636 3/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6890763 0.85 NQO1 (0.73) NQO1CA2CA12CA1CA7
SCHEMBL9097639 0.85 NQO1 (0.58) NQO1CA2CA12CA1CA7
SCHEMBL1061836 0.81 NQO1 (1.00) NQO1CA2CA12CA1CA7
SCHEMBL29886321 0.81 NQO1 (1.00) NQO1CA2CA12CA1CA7
SCHEMBL11149087 0.79 ACHE (0.62) NQO1ACHEIDO1EP300KAT8
SCHEMBL1402631 0.79 NQO1 (0.52) NQO1CA2CA12CA1CA7
SCHEMBL30003276 0.79 ACHE (0.62) NQO1ACHEIDO1EP300KAT8
SCHEMBL15805518 0.79 IMPDH2 (0.64) NQO1ALDH1A1IMPDH2IMPDH1KDM4E
SCHEMBL29380721 0.78 IDO1 (0.73) NQO1CA2CA12CA1CA7
SCHEMBL419307 0.78 IDO1 (0.73) NQO1CA2CA12CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION 2024-10-10 US disclosed
US-12036515-B2 Thin-film composite membrane and methods of making and using the same THE PENN STATE RESEARCH FOUNDATION (PA) 2024-07-16 US disclosed
US-20210370240-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION 2021-12-02 US disclosed
EP-3860743-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME The Penn State Research Foundation (US) 2021-08-11 EP disclosed
WO-2020072594-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION (US) 2020-04-09 WO disclosed
US-7655809-B2 Compounds comprising a linear series of five fused carbon rings, and preparation thereof UNIVERSITY OF OTTAWA (CA) 2010-02-02 US disclosed
US-7655809-B2 Compounds comprising a linear series of five fused carbon rings, and preparation thereof UNIVERSITY OF OTTAWA (CA) 2010-02-02 US disclosed
US-7655809-B2 Compounds comprising a linear series of five fused carbon rings, and preparation thereof UNIVERSITY OF OTTAWA (CA) 2010-02-02 US disclosed
US-20050274945-A1 Compounds comprising a linear series of five fused carbon rings, and preparation thereof UNIVERSITY OF OTTAWA (CA) 2005-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME PORCN, MLEC, FLOT1 NQO1 4335/4885CA2 3089/4885CA12 1547/4885
US-12036515-B2 Thin-film composite membrane and methods of making and using the same PORCN, MLEC, FLOT1 NQO1 4335/4885CA2 3089/4885CA12 1547/4885
US-20210370240-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME PORCN, MLEC, FLOT1 NQO1 4335/4885CA2 3089/4885CA12 1547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.