Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22263304 | 0.84 | PTGES (0.65) | PTGESALOX5PTGS1ALOX5APPTGS2 | |
| SCHEMBL4086803 | 0.82 | PTGES (0.80) | PTGESALOX5PTGS1ALOX5APPTGS2 | |
| SCHEMBL6505087 | 0.81 | PTGES (0.78) | PTGESALOX5PTGS1ALOX5APPTGS2 | |
| SCHEMBL18782717 | 0.81 | PTGES (0.78) | PTGESALOX5PTGS1ALOX5APPTGS2 | |
| SCHEMBL3984072 | 0.81 | PTGES (0.77) | PTGESALOX5PTGS1ALOX5APPTGS2 | |
| SCHEMBL17208128 | 0.80 | PTGES (0.80) | PTGESALOX5PTGS1ALOX5APPTGS2 | |
| Licofelone SCHEMBL237833 | 0.80 | ALOX5 (1.00) | PTGESALOX5PTGS1ALOX5APPTGS2 | |
| SCHEMBL6502826 | 0.80 | PTGES (0.76) | PTGESALOX5PTGS1ALOX5APPTGS2 | |
| SCHEMBL13697422 | 0.79 | PTGES (0.85) | PTGESALOX5PTGS1ALOX5APPTGS2 | |
| SCHEMBL18782759 | 0.79 | PTGES (0.74) | PTGESALOX5PTGS1ALOX5APPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239473-A1 | NEW DERIVATIVES OF LICOFELONE | ALBRECHT WOLFGANG (DE) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239473-A1 | NEW DERIVATIVES OF LICOFELONE | CYP51A1, CYP3A5, LITAF | PTGES 265/4885ALOX5 38/4885PTGS1 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.