Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 10/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769449 | 0.85 | P2RX4 (0.43) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 | |
| SCHEMBL6110761 | 0.84 | P2RX4 (0.46) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 | |
| SCHEMBL205655 | 0.83 | SMN1; SMN2 (0.53) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 | |
| SCHEMBL29549990 | 0.83 | SMN1; SMN2 (0.53) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 | |
| SCHEMBL8768858 | 0.79 | P2RX4 (0.43) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 | |
| SCHEMBL6110401 | 0.78 | P2RX4 (0.64) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 | |
| SCHEMBL27785934 | 0.77 | P2RX4 (0.58) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 | |
| SCHEMBL6110992 | 0.76 | SMN1; SMN2 (0.44) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 | |
| SCHEMBL411007 | 0.76 | SMN1; SMN2 (0.44) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 | |
| SCHEMBL29639604 | 0.76 | SMN1; SMN2 (0.44) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11414411-B2 | Chemical process for manufacturing monobactam antibiotic and intermediates thereof | NOVARTIS AG (CH) | 2022-08-16 | — | — | US | disclosed |
| US-20200239461-A1 | CHEMICAL PROCESS FOR MANUFACTURING MONOBACTAM ANTIBIOTIC AND INTERMEDIATES THEREOF | SUZHOU NOVARTIS PHARMA TECHNOLOGY CO., LTD. (CN) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11414411-B2 | Chemical process for manufacturing monobactam antibiotic and intermediates thereof | SRR, DCXR, JMJD6 | P2RX4 2256/4885SMN1; SMN2 3344/4885LMNA 4393/4885 |
| US-20200239461-A1 | CHEMICAL PROCESS FOR MANUFACTURING MONOBACTAM ANTIBIOTIC AND INTERMEDIATES THEREOF | SRR, DCXR, JMJD6 | P2RX4 2256/4885SMN1; SMN2 3344/4885LMNA 4393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.