Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639604 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAP2RX4ALDH1A1BCHE | |
| SCHEMBL29549990 | 0.89 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAP2RX4ALDH1A1BCHE | |
| SCHEMBL205655 | 0.89 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAP2RX4ALDH1A1BCHE | |
| SCHEMBL6110992 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAP2RX4ALDH1A1BCHE | |
| SCHEMBL3638042 | 0.87 | LMNA (0.69) | SMN1; SMN2LMNAP2RX4ALDH1A1BCHE | |
| SCHEMBL3719677 | 0.86 | BCHE (0.50) | SMN1; SMN2LMNAP2RX4ALDH1A1BCHE | |
| SCHEMBL6110401 | 0.79 | P2RX4 (0.64) | SMN1; SMN2LMNAP2RX4ALDH1A1P2RX1 | |
| SCHEMBL27785934 | 0.78 | P2RX4 (0.58) | SMN1; SMN2LMNAP2RX4BCHEP2RX1 | |
| SCHEMBL28802473 | 0.77 | P2RX4 (0.63) | SMN1; SMN2P2RX4ALDH1A1P2RX1P2RX3 | |
| SCHEMBL22264116 | 0.76 | P2RX4 (0.41) | SMN1; SMN2LMNAP2RX4ALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339906-A1 | A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF | PI INDUSTRIES LTD. (IN) | 2023-10-26 | — | — | US | claimed |
| CN-112830984-B | Design and preparation method of non-woven fabric material capable of being disinfected by chlorine dioxide | 厦门市添孚卫生科技有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-111094281-B | Chemical process for preparing monolactam antibiotics and intermediates thereof | 诺华股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| US-11414411-B2 | Chemical process for manufacturing monobactam antibiotic and intermediates thereof | NOVARTIS AG (CH) | 2022-08-16 | — | — | US | claimed |
| EP-3661933-B1 | PROCESS FOR PREPARING 1-(((Z)-(1-(2-AMINOTHIAZOL-4-YL)-2-OXO-2-(((3S,4R)-2-OXO-4-((2-OXOOXAZOLIDIN-3-YL)METHYL)-1-SULFOAZETIDIN-3- YL)AMINO)ETHYLIDENE)AMINO)OXY)CYCLOPROPANE CARBOXYLIC ACID | NOVARTIS AG (CH) | 2022-03-23 | — | — | EP | claimed |
| EP-3927685-A1 | A PROCESS FOR THE SYNTHESIS ANTHRANILIC DIAMIDE COMPOUNDS AND INTERMEDIATES THEREOF | PI Industries Ltd. (IN) | 2021-12-29 | — | — | EP | claimed |
| CN-112830984-A | Design and preparation method of novel non-woven fabric material capable of being disinfected by chlorine dioxide | 厦门市添孚卫生科技有限公司 | 2021-05-25 | — | — | CN | claimed |
| US-20200239461-A1 | CHEMICAL PROCESS FOR MANUFACTURING MONOBACTAM ANTIBIOTIC AND INTERMEDIATES THEREOF | SUZHOU NOVARTIS PHARMA TECHNOLOGY CO., LTD. (CN) | 2020-07-30 | — | — | US | claimed |
| CN-111094281-A | Chemical process for the preparation of monobactam antibiotics and intermediates thereof | 诺华股份有限公司 | 2020-05-01 | — | — | CN | claimed |
| EP-1684816-B1 | METHODS OF PREPARING CROSSLINKED MATERIALS AND BIOPROSTHETIC DEVICES | MEDTRONIC INC (US) | 2009-05-06 | — | — | EP | claimed |
| EP-1641754-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF (1R, 2S, 5S)-3- AZABICYCLO[ 3, 1, 0]HEXANE-2-CARBOXAMIDE, N- [3-AMINO -1-(CYCLOBUTYLMETHYL)-2, 3-DIOXOPROPYL] ]-3- [ (2S)- 2-[[[1, 1-DIMETHYLETHYL ]AMINO]CARBONYLA MINO ]-3, 3-DIMETHYL-1-OXOBUTYL] -6, 6-DIMETHYL | SCHERING CORP (US) | 2008-03-26 | — | — | EP | claimed |
| US-7326795-B2 | Process and intermediates for the preparation of (1R,2S,5S)-3-azabicyclo[3,1,0]hexane-2-carboxamide, N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[1,1-dimethylethyl]amino]carbonylamino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl | SCHERING CORPORATION (US) | 2008-02-05 | — | — | US | claimed |
| EP-1641754-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF (1R, 2S, 5S)-3- AZABICYCLO[ 3, 1, 0]HEXANE-2-CARBOXAMIDE, N- [3-AMINO -1-(CYCLOBUTYLMETHYL)-2, 3-DIOXOPROPYL] ]-3- [ (2S)- 2-[[[1, 1-DIMETHYLETHYL ]AMINO]CARBONYLA MINO ]-3, 3-DIMETHYL-1-OXOBUTYL] -6, 6-DIMETHYL | SCHERING CORPORATION (US) | 2006-04-05 | — | — | EP | claimed |
| EP-1556039-A2 | PROCESS FOR THE PREPARATION OF TRI-NITROGEN CONTAINING HETEROARYL-DIAMINE DERIVATIVES USEFUL AS PHARMACEUTICAL AGENTS AND METHODS OF PRODUCING PHARMACEUTICAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-07-27 | — | — | EP | claimed |
| US-20050059800-A1 | Process and intermediates for the preparation of (1R,2S,5S)-3-azabicyclo[3,1,0]hexane-2-carboxamide, N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[1,1-dimethylethyl]amino]carbonylamino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl | SCHERING CORPORATION | 2005-03-17 | — | — | US | claimed |
| WO-2004113294-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF (1R, 2S, 5S)-3-AZABICYCLO[3, 1, 0]HEXANE-2-CARBOXAMIDE, N-[3-AMINO-1-(CYCLOBUTYLMETHYL)-2, 3-DIOXOPROPYL] ]-3-[(2S)-2-[[[1, 1-DIMETHYLETHYL]AMINO]CARBONYLAMINO]-3, 3-DIMETHYL-1-OXOBUTYL]-6, 6-DIMETHYL | SCHERING CORPORATION (US) | 2004-12-29 | — | — | WO | claimed |
| WO-2004032875-A2 | PROCESS FOR THE PREPARATION OF TRI-NITROGEN CONTAINING HETEROARYL-DIAMINE DERIVATIVES USEFUL AS PHARMACEUTICAL AGENTS AND METHODS OF PRODUCING PHARMACEUTICAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-22 | — | — | WO | claimed |
| US-20250152734-A1 | USES AND FORMULATIONS OF CAMPTOTHECIN (CPT)-CONTAINING NANOPARTICLES | DANTARI INC (US) | 2025-05-15 | — | — | US | disclosed |
| US-4076822-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1978-02-28 | — | — | US | disclosed |
| US-3980657-A | FIBRINOLYTICS, THROMBOLYTICS, ANTIPHLOGISTICS, ANALGESICS | CIBA-GEIGY CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11414411-B2 | Chemical process for manufacturing monobactam antibiotic and intermediates thereof | SRR, DCXR, JMJD6 | SMN1; SMN2 3344/4885LMNA 4393/4885P2RX4 2256/4885 |
| US-20050059800-A1 | Process and intermediates for the preparation of (1R,2S,5S)-3-azabicyclo[3,1,0]hexane-2-carboxamide, N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[1,1-dimethylethyl]amino]carbonylamino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl | AZI2, ALKBH1, ALKBH5 | SMN1; SMN2 535/4885LMNA 1643/4885P2RX4 1818/4885 |
| US-20200239461-A1 | CHEMICAL PROCESS FOR MANUFACTURING MONOBACTAM ANTIBIOTIC AND INTERMEDIATES THEREOF | SRR, DCXR, JMJD6 | SMN1; SMN2 3344/4885LMNA 4393/4885P2RX4 2256/4885 |
| US-20250152734-A1 | USES AND FORMULATIONS OF CAMPTOTHECIN (CPT)-CONTAINING NANOPARTICLES | MUC1, TOP2A, TOP1 | SMN1; SMN2 3465/4885LMNA 1277/4885P2RX4 4147/4885 |
| US-20230339906-A1 | A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF | ASS1, ARG1, NQO2 | SMN1; SMN2 4835/4885LMNA 3246/4885P2RX4 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.