SCHEMBL22265083

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4138404	0.86	PARL (0.41)	PARLPSIP1HSD11B1ALDH1A1KMT2A
	SCHEMBL28268959	0.85	ALDH1A1 (0.41)	ALDH1A1KMT2AMEN1CYP1A2CYP3A4
	SCHEMBL22265082	0.84	PARL (0.40)	PARLPSIP1HSD11B1ALDH1A1KMT2A
	SCHEMBL3447252	0.83	PSIP1 (0.45)	PARLPSIP1HSD11B1ALDH1A1ATM
	SCHEMBL22265192	0.83	PARL (0.39)	PARLPSIP1HSD11B1ALDH1A1KMT2A
	SCHEMBL22265193	0.83	TDP1 (0.39)	PARLPSIP1ALDH1A1ATMKMT2A
	SCHEMBL2057595	0.82	PSIP1 (0.43)	PARLPSIP1HSD11B1ALDH1A1ATM
	SCHEMBL5590961	0.82	PSIP1 (0.43)	PARLPSIP1HSD11B1ALDH1A1ATM
	SCHEMBL2270234	0.82	CA1 (0.43)	PARLPSIP1HSD11B1ALDH1A1KMT2A
	SCHEMBL25402625	0.79	HSD11B1 (0.40)	HSD11B1ALDH1A1KMT2AABCC9ABCC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.