Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23615418 | 0.85 | FOLH1 (0.40) | FOLH1CTSKNMT2NMT1SIRT6 | |
| SCHEMBL14961163 | 0.77 | SIRT6 (0.43) | FOLH1NMT2NMT1SIRT6SIRT1 | |
| SCHEMBL21566743 | 0.77 | SIRT6 (0.54) | FOLH1SIRT6SIRT1 | |
| SCHEMBL14961162 | 0.77 | SIRT6 (0.43) | FOLH1NMT2NMT1SIRT6SIRT1 | |
| SCHEMBL16557402 | 0.77 | SIRT6 (0.54) | FOLH1SIRT6SIRT1 | |
| SCHEMBL23053207 | 0.75 | NMT1 (0.43) | FOLH1NMT2NMT1SIRT6SIRT1 | |
| SCHEMBL31015746 | 0.74 | FOLH1 (0.49) | FOLH1CPB2SLC6A5 | |
| SCHEMBL24453587 | 0.73 | NMT2 (0.37) | FOLH1NMT2NMT1SIRT6SIRT1 | |
| SCHEMBL23682447 | 0.73 | NMT2 (0.37) | FOLH1NMT2NMT1SIRT6SIRT1 | |
| SCHEMBL20435279 | 0.73 | FOLH1 (0.41) | FOLH1NMT2NMT1SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723776-B1 | Apelin peptides and uses thereof | THE GOVERNERS OF THE UNIVERSITY OF ALBERTA (CA) | 2020-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10723776-B1 | Apelin peptides and uses thereof | APLNR, MME, ANPEP | FOLH1 327/4885CTSK 150/4885NMT2 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.