Water

Water

SCHEMBL222676

O.[Au].[Ni]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL2845482 0.87
Water SCHEMBL2721093 0.82
Water SCHEMBL2479241 0.82
Water SCHEMBL339061 0.82
Water SCHEMBL10695512 0.82
Water SCHEMBL1065284 0.82
Water SCHEMBL9751635 0.82
Water SCHEMBL7168086 0.82
Water SCHEMBL22041615 0.82
Water SCHEMBL526976 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2287930-B1 Light emitting diode including barrier layers and manufacturing method therefor CREE INC (US) 2019-06-05 EP claimed
EP-1523776-B1 LIGHT EMITTING DIODE INCLUDING BARRIER LAYERS AND MANUFACTURING METHODS THEREFOR CREE INC (US) 2019-05-15 EP claimed
CN-103647010-B A kind of preparation method of high-power LED chip 湘能华磊光电股份有限公司 2016-08-31 CN claimed
CN-103219352-B LED combination chip of array architecture and preparation method thereof HUALEI OPTOELECTRONIC CORPORATION (CN) 2015-10-14 CN claimed
EP-1771893-B1 ULTRA-THIN OHMIC CONTACTS FOR P-TYPE NITRIDE LIGHT EMITTING DEVICES AND METHODS OF FORMING CREE INC (US) 2015-03-18 EP claimed
CN-101976717-B Light emitting diodes including modifications for light extraction and manufacturing methods therefor CREE INC 2014-08-27 CN claimed
US-8680551-B1 High power ultraviolet light sources and method of fabricating the same NITEK, INC. (US) 2014-03-25 US claimed
CN-103647010-A Manufacturing method of high power LED chip HUNAN HUALEI OPTOELECTRONIC CORP 2014-03-19 CN claimed
CN-103337577-A Light emitting device with light emission gain WALSIN LIHWA CORP 2013-10-02 CN claimed
CN-103219352-A LED (Light Emitting Diode) combined chip in array structure and manufacturing method thereof HUNAN HUALEI OPTOELECTRONIC CORP 2013-07-24 CN claimed
EP-1382073-A2 LIGHT EMITTING DIODES INCLUDING MODIFICATIONS FOR LIGHT EXTRACTION AND MANUFACTURING METHODS THEREFOR CREE, INC. (US) 2004-01-21 EP claimed
WO-2003098713-A1 LIGHT-EMITTING DIODE WITH SILICON CARBIDE SUBSTRATE LUMEI OPTOELECTRONICS CORPORATION (US) 2003-11-27 WO claimed
US-20030214807-A1 Light-emitting diode with silicon carbide substrate DALIAN MEIMING EPITAXY TECHNOLOGY CO., LTD. (CN) 2003-11-20 US claimed
WO-2003010817-A2 LIGHT EMITTING DIODES INCLUDING MODIFICATIONS FOR SUBMOUNT BONDING AND MANUFACTURING METHODS THEREFOR CREE, INC. (US) 2003-02-06 WO claimed
US-20030015721-A1 Light emitting diodes including modifications for submount bonding and manufacturing methods therefor CREELED, INC. 2003-01-23 US claimed
US-20020130327-A1 LIGHT EMITTING DIODES WITH SPREADING AND IMPROVING LIGHT EMITTING AREA UNI LIGHT TECHNOLOGY INC. (TW) 2002-09-19 US claimed
US-20020123164-A1 Light emitting diodes including modifications for light extraction and manufacturing methods therefor CREELED, INC. 2002-09-05 US claimed
US-6445007-B1 Light emitting diodes with spreading and improving light emitting area UNI LIGHT TECHNOLOGY INC. (TW) 2002-09-03 US claimed
WO-2002061847-A2 LIGHT EMITTING DIODES INCLUDING MODIFICATIONS FOR LIGHT EXTRACTION AND MANUFACTURING METHODS THEREFOR CREE, INC. (US) 2002-08-08 WO claimed
CN-1354528-A Self-passinvating non-planar junction subgroup III nitride semi-conductor device and its making method INST OF SEMICONDCUTOR CHINESE (CN) 2002-06-19 CN claimed