Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22271025 | 0.78 | FFAR1 (0.37) | FFAR1F2KCNH2GRIN2BADRB1 | |
| SCHEMBL19205697 | 0.77 | KCNJ5 (0.48) | MAPTADRB1ADRB3RAB9A | |
| SCHEMBL22271065 | 0.77 | HTR7 (0.42) | GAAMAPTALDH1A1L3MBTL1RAB9A | |
| SCHEMBL22270650 | 0.72 | TRPV1 (0.37) | MAPTMAOBALDH1A1L3MBTL1 | |
| SCHEMBL18448801 | 0.70 | MPO (0.44) | MAOBMAOA | |
| SCHEMBL22271075 | 0.70 | RXRA (0.31) | — | |
| SCHEMBL18449672 | 0.66 | KMT2A (0.47) | MAPTMAOBALDH1A1L3MBTL1RAB9A | |
| SCHEMBL22271071 | 0.61 | CNR1 (0.39) | CYP3A4 | |
| SCHEMBL26268493 | 0.61 | TAAR1 (0.62) | GAAMAPTFFAR1KCNH2THRB | |
| SCHEMBL3908446 | 0.60 | TAAR1 (0.60) | MAPTFFAR1MAOBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |