Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | PPIF | P30405 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270886 | 0.81 | L3MBTL1 (0.35) | PPIF | |
| SCHEMBL22270591 | 0.80 | PSMB5 (0.33) | — | |
| SCHEMBL22270668 | 0.74 | KDR (0.36) | — | |
| SCHEMBL22270867 | 0.73 | WNT3A (0.32) | — | |
| SCHEMBL22271062 | 0.70 | LPAR1 (0.35) | — | |
| SCHEMBL28641213 | 0.70 | RORC (0.40) | — | |
| SCHEMBL22270597 | 0.70 | GAA (0.40) | — | |
| SCHEMBL22270885 | 0.70 | RORC (0.35) | — | |
| SCHEMBL22270602 | 0.70 | TPH1 (0.35) | — | |
| SCHEMBL18484585 | 0.70 | KDM4A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |