Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 7/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18447913 | 0.83 | LMNA (0.43) | CSF1RPTGDR2PDE5AEGFRMETAP2 | |
| SCHEMBL22271053 | 0.72 | HPGD (0.46) | CYP1A2CYP3A4CYP2D6CYP2C19LIMK2 | |
| SCHEMBL18485898 | 0.70 | RAB9A (0.54) | CSF1RPDE5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21639691 | 0.66 | RAB9A (0.49) | CSF1RPDE5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12574994 | 0.66 | BRD4 (0.43) | CSF1RPDE5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2024425 | 0.66 | GABRA1 (0.44) | CSF1RPDE5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18483421 | 0.66 | TRPV1 (0.44) | CYP2C9SMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL12889093 | 0.65 | ALDH1A1 (0.54) | CSF1RPDE5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9379285 | 0.65 | PDE5A (0.52) | CSF1RPDE5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18483362 | 0.65 | ALDH1A1 (0.38) | LIMK2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |