Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456842 | 0.84 | DGAT1 (0.40) | DGAT1DPP4FAPHTR2BUSP30 | |
| SCHEMBL1929948 | 0.84 | DGAT1 (0.40) | DGAT1DPP4FAPHTR2BUSP30 | |
| SCHEMBL2282218 | 0.71 | USP30 (0.53) | USP30 | |
| SCHEMBL3223565 | 0.70 | DGAT1 (0.40) | DGAT1HTR2BUSP30KCNH2PDE10A | |
| SCHEMBL6881971 | 0.70 | HTR2B (0.41) | DGAT1HTR2BUSP30KCNH2PDE10A | |
| SCHEMBL2229563 | 0.70 | HTR2B (0.41) | DGAT1HTR2BUSP30KCNH2PDE10A | |
| SCHEMBL1550240 | 0.68 | HIF1A (0.36) | DGAT1HTR2BUSP30KCNH2CHRNA7 | |
| SCHEMBL12553013 | 0.65 | CASP1 (0.40) | — | |
| SCHEMBL24198723 | 0.61 | HIF1A (0.49) | DGAT1 | |
| SCHEMBL24757713 | 0.60 | VHL (0.51) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091407-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLP (US) | 2011-07-28 | — | — | WO | disclosed |