Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | METTL3 | Q86U44 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12517358 | 0.81 | GBA1 (0.51) | GAAL3MBTL1KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL2229679 | 0.80 | GBA1 (0.50) | GAAL3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL2227543 | 0.79 | ALDH1A1 (0.52) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2228484 | 0.78 | MAPT (0.44) | GAAMETTL3MAPTL3MBTL1KDM4E | |
| SCHEMBL2227475 | 0.78 | MAPT (0.52) | GAAMETTL3MAPTL3MBTL1KDM4E | |
| SCHEMBL2287837 | 0.75 | KAT2B (0.46) | MAPTL3MBTL1KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL2227870 | 0.73 | HPGD (0.44) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL12517360 | 0.71 | HPGD (0.37) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2229253 | 0.70 | RAB9A (0.47) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2227877 | 0.69 | METTL3 (0.41) | GAAMETTL3MAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | disclosed |