Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 15/20 | 0.43 |
| ▸ | METTL14 | Q9HCE5 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229604 | 0.78 | GAA (0.40) | MAPTMETTL3ALDH1A1KDM4ELMNA | |
| SCHEMBL12517668 | 0.76 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL2228748 | 0.76 | ALDH1A1 (0.38) | MAPTMETTL3ALDH1A1KDM4ELMNA | |
| SCHEMBL2227475 | 0.76 | MAPT (0.52) | MAPTMETTL3ALDH1A1KDM4ELMNA | |
| SCHEMBL2229253 | 0.75 | RAB9A (0.47) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL2287837 | 0.74 | KAT2B (0.46) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL2227877 | 0.73 | METTL3 (0.41) | MAPTMETTL3METTL14ALDH1A1KDM4E | |
| SCHEMBL12517354 | 0.71 | ALDH1A1 (0.46) | MAPTMETTL3METTL14ALDH1A1KDM4E | |
| SCHEMBL12517358 | 0.71 | GBA1 (0.51) | ALDH1A1KDM4ELMNAL3MBTL1HPGD | |
| SCHEMBL12517359 | 0.71 | ALDH1A1 (0.47) | MAPTMETTL3METTL14ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | disclosed |