SCHEMBL22277295

SCHEMBL22277295

C/C=C/CCC1CCC(C2CCC(C3CCC(OCc4ccc(CCC)c(F)c4F)CC3)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.32
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22277569 0.88 NAAA (0.35)
SCHEMBL22277593 0.88 CTSL (0.32) CTSLCTSSCTSK
SCHEMBL22277294 0.87 HTR1A (0.33) CTSLCTSSCTSK
SCHEMBL22277611 0.87 CTSL (0.31) CTSLCTSSCTSK
SCHEMBL22277650 0.82 SPHK1 (0.33)
SCHEMBL22277625 0.80
SCHEMBL22277644 0.79 CNR2 (0.32)
SCHEMBL22277520 0.79 CTSL (0.34) CTSLCTSSCTSK
SCHEMBL13922534 0.78 CTSL (0.31) CTSLCTSSCTSK
SCHEMBL22277623 0.78 ALOX5 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200239775-A1 TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-07-30 US disclosed