Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277593 | 0.88 | CTSL (0.32) | HTR1ACTSLCTSSCTSK | |
| SCHEMBL22277636 | 0.87 | NAAA (0.38) | HTR1ATLR4 | |
| SCHEMBL22277295 | 0.87 | CTSL (0.32) | CTSLCTSSCTSK | |
| SCHEMBL20346141 | 0.84 | TLR4 (0.35) | CTSLCTSSCTSKTLR4 | |
| SCHEMBL22277586 | 0.84 | TLR4 (0.35) | CTSLCTSSCTSKTLR4 | |
| SCHEMBL22277220 | 0.82 | GPR119 (0.36) | — | |
| SCHEMBL22277344 | 0.82 | GPR119 (0.36) | — | |
| SCHEMBL12740198 | 0.81 | HTR1A (0.32) | HTR1A | |
| SCHEMBL12736585 | 0.81 | HTR1A (0.32) | HTR1A | |
| SCHEMBL9406055 | 0.81 | RIPK1 (0.38) | CTSLCTSSCTSKTLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |