Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22279042 | 0.85 | P4HTM (0.47) | P4HTMALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL22279048 | 0.84 | GAA (0.55) | KMT2AP4HTMALDH1A1L3MBTL1GAA | |
| SCHEMBL22279049 | 0.82 | P4HTM (0.51) | KMT2AP4HTMALDH1A1L3MBTL1GAA | |
| SCHEMBL22279043 | 0.81 | P4HTM (0.50) | KMT2AP4HTMALDH1A1L3MBTL1GAA | |
| SCHEMBL4737532 | 0.78 | GAA (0.51) | KMT2AALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL22279046 | 0.74 | GAA (0.46) | P4HTML3MBTL1GAAMAPTSMN1; SMN2 | |
| SCHEMBL3058922 | 0.73 | HRH4 (0.53) | KMT2AL3MBTL1GAAMAPTSMN1; SMN2 | |
| SCHEMBL4738295 | 0.73 | BPTF (0.51) | P4HTML3MBTL1GAAMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3826981 | 0.72 | HRH4 (0.52) | KMT2AL3MBTL1GAAMAPTSMN1; SMN2 | |
| SCHEMBL3063613 | 0.71 | DRD2 (0.54) | ALDH1A1L3MBTL1GAAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020151686-A1 | N-HETEROARYL SULFONAMIDE DERIVATIVE, PREPARATION AND USE THEREOF IN TREATMENT OF AUTOIMMUNE DISEASES | 杭州壹瑞医药科技有限公司 | 2020-07-30 | — | — | WO | disclosed |