Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22279048 | 0.94 | GAA (0.55) | GAAMAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL3058922 | 0.85 | HRH4 (0.53) | GAAMAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL4738295 | 0.85 | BPTF (0.51) | GAAMAPTL3MBTL1KDM4EALOX12 | |
| SCHEMBL1845770 | 0.84 | MAPT (0.70) | GAAMAPTRAB9ANPC1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3826981 | 0.84 | HRH4 (0.52) | GAAMAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL3063613 | 0.82 | DRD2 (0.54) | GAAL3MBTL1KDM4EAURKAABL1 | |
| SCHEMBL22279049 | 0.81 | P4HTM (0.51) | GAAMAPTL3MBTL1KDM4EALOX12 | |
| SCHEMBL22279043 | 0.80 | P4HTM (0.50) | GAAMAPTL3MBTL1KDM4EALOX12 | |
| SCHEMBL22279054 | 0.80 | KDM4E (0.57) | GAAMAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL2449960 | 0.79 | RAB9A (0.70) | GAAMAPTRAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |