SCHEMBL22279610

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14567205	0.86	ELANE (0.46)	CA12CA1CA2CA7CA9
	SCHEMBL22941003	0.83	KDM4E (0.37)	CA12CA1CA2CA7CA9
	SCHEMBL22279612	0.79	KDM4E (0.59)	KMT2AALDH1A1KDM4EHPGDMAPK1
	SCHEMBL22279621	0.79	PLA2G2A (0.41)	CA12CA1CA2CA7CA9
	SCHEMBL14567193	0.78	GAA (0.38)	CA12CA1CA2CA7CA9
	SCHEMBL22986758	0.72	ELANE (0.37)	ALDH1A1ALOX15KDM4EELANEGAA
	SCHEMBL21276510	0.72	ELANE (0.53)	KMT2AALDH1A1ALOX15MEN1HPGD
	SCHEMBL22279461	0.71	KMT2A (0.56)	CA1CA2KMT2AALDH1A1MAPK1
	SCHEMBL22279609	0.71	CA12 (0.33)	CA12CA1CA2CA7CA9
	SCHEMBL22279456	0.71	ALDH1A1 (0.49)	KMT2AALDH1A1KDM4EMEN1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.