Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280466 | 0.86 | SPHK2 (0.49) | S1PR1 | |
| SCHEMBL22280481 | 0.77 | PPARD (0.47) | FFAR1PPARDPPARAS1PR1S1PR3 | |
| SCHEMBL19430448 | 0.72 | NR1H4 (0.43) | FFAR1PPARDPPARAMAOBADORA2B | |
| SCHEMBL22280642 | 0.72 | S1PR1 (0.39) | HDAC1HDAC6S1PR1 | |
| SCHEMBL26095786 | 0.72 | SMPD1 (0.63) | SMPD1FFAR1PPARDPPARAHDAC1 | |
| SCHEMBL9351372 | 0.70 | RAB9A (0.51) | SMPD1MAOB | |
| SCHEMBL9351935 | 0.70 | RAB9A (0.51) | SMPD1MAOB | |
| SCHEMBL9352120 | 0.70 | RAB9A (0.51) | SMPD1MAOB | |
| SCHEMBL9347677 | 0.70 | RAB9A (0.51) | SMPD1MAOB | |
| SCHEMBL13099319 | 0.70 | SMPD1 (0.60) | SMPD1FFAR1PPARDPPARAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154431-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | LYNCH KEVIN R (US) | 2020-07-30 | — | — | WO | disclosed |