SCHEMBL22283365

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5034071	0.87	ALDH1A1 (0.42)	TDP1LMNATSHRALDH1A1HPGD
	SCHEMBL1526858	0.85	KDM4E (0.45)	TDP1LMNATSHRALDH1A1HPGD
	SCHEMBL22283400	0.84	TDP1 (0.46)	TDP1LMNATSHRADRB2ADRB1
	SCHEMBL22283429	0.84	CYP1A2 (0.43)	TDP1LMNATSHRADRB2ADRB1
	SCHEMBL3042617	0.83	ADRA1A (0.37)	TDP1LMNATSHRALDH1A1HPGD
	SCHEMBL22283528	0.81	TDP1 (0.41)	TDP1LMNATSHRADRB2ADRB1
	SCHEMBL5510637	0.81	CYP2D6 (0.36)	TDP1LMNAADRB2ADRB1ADRB3
	SCHEMBL5329620	0.81	CTSK (0.31)	TDP1LMNAALDH1A1CYP3A4
	SCHEMBL22283392	0.80	CA12 (0.41)	TDP1LMNATSHRADRB2ADRB1
	SCHEMBL24691225	0.78	LMNA (0.56)	TDP1LMNATSHRADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.