Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.83 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.83 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.73 |
| ▸ | CA12 | O43570 | 1/20 | 0.73 |
| ▸ | PDE5A | O76074 | 1/20 | 0.73 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.73 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.73 |
| ▸ | CA2 | P00918 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | CA3 | P07451 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352145 | 0.91 | PTGS2 (1.00) | PTGESPTGS2PTGS1PDPK1HDAC3 | |
| SCHEMBL16025998 | 0.91 | PTGES (0.83) | PTGESPTGS2PTGS1PDPK1HDAC3 | |
| SCHEMBL30149115 | 0.91 | PTGS2 (1.00) | PTGESPTGS2PTGS1PDPK1HDAC3 | |
| SCHEMBL16025997 | 0.89 | PTGES (0.80) | PTGESPTGS2PTGS1PDPK1HDAC3 | |
| SCHEMBL16026002 | 0.88 | PTGES (0.78) | PTGESPTGS2PTGS1PDPK1HDAC3 | |
| SCHEMBL6013935 | 0.87 | PTGS2 (0.81) | PTGESPTGS2PTGS1PDPK1HDAC3 | |
| SCHEMBL3239998 | 0.87 | PTGS2 (1.00) | PTGESPTGS2PTGS1PDPK1HDAC3 | |
| SCHEMBL16025934 | 0.87 | PTGES (0.77) | PTGESPTGS2PTGS1PDPK1HDAC3 | |
| SCHEMBL6013961 | 0.86 | PTGS2 (0.80) | PTGESPTGS2PTGS1PDPK1HDAC3 | |
| SCHEMBL16026023 | 0.86 | PTGES (0.75) | PTGESPTGS2PTGS1PDPK1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230405125-A1 | TREATMENT OF RECURRENT GIOBLASTOMA WITH PERILLYL ALCOHOL | Neonc Technologies, Inc. | 2023-12-21 | — | — | US | claimed |
| EP-4243794-A1 | TREATMENT OF RECURRENT GIOBLASTOMA WITH PERILLYL ALCOHOL | Neonc Technologies, Inc. (US) | 2023-09-20 | — | — | EP | claimed |
| WO-2022104041-A1 | TREATMENT OF RECURRENT GIOBLASTOMA WITH PERILLYL ALCOHOL | Neonc Technologies, Inc. (US) | 2022-05-19 | — | — | WO | claimed |
| US-8637564-B2 | Methods and compositions for inducing apoptosis by stimulating ER stress | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-01-28 | — | — | US | claimed |
| US-20110318837-A1 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS BY STIMULATING ER STRESS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-12-29 | — | — | US | claimed |
| US-7981917-B2 | Methods and compositions for including apoptosis by stimulating ER stress | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-07-19 | — | — | US | claimed |
| US-20090062227-A1 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS BY STIMULATING ER STRESS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-03-05 | — | — | US | claimed |
| US-20060142368-A1 | Compounds and methods for inducing apoptosis in proliferating cells | MRDC | 2006-06-29 | — | — | US | claimed |
| EP-1499597-A4 | COMPOUNDS AND METHODS FOR INDUCING APOPTOSIS IN PROLIFERATING CELLS | UNIV OHIO STATE RES FOUND (US) | 2006-01-25 | — | — | EP | claimed |
| EP-1499597-A2 | COMPOUNDS AND METHODS FOR INDUCING APOPTOSIS IN PROLIFERATING CELLS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-01-26 | — | — | EP | claimed |
| US-20030236294-A1 | Compounds and methods for inducing apoptosis in proliferating cells | NIH - DEITR | 2003-12-25 | — | — | US | claimed |
| WO-2003086287-A2 | COMPOUNDS AND METHODS FOR INDUCING APOPTOSIS IN PROLIFERATING CELLS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2003-10-23 | — | — | WO | claimed |
| EP-3244930-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES | UNIV SOUTHERN CALIFORNIA (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20260069587-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2026-03-12 | — | — | US | disclosed |
| EP-4656641-A2 | METHODS AND DEVICES FOR USING ISOPERILLYL ALCOHOL | University of Southern California (US) | 2025-12-03 | — | — | EP | disclosed |
| US-20250332262-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2025-10-30 | — | — | US | disclosed |
| EP-1499597-A4 | COMPOUNDS AND METHODS FOR INDUCING APOPTOSIS IN PROLIFERATING CELLS | UNIV OHIO STATE RES FOUND (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1499597-A2 | COMPOUNDS AND METHODS FOR INDUCING APOPTOSIS IN PROLIFERATING CELLS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-01-26 | — | — | EP | disclosed |
| US-20030236294-A1 | Compounds and methods for inducing apoptosis in proliferating cells | NIH - DEITR | 2003-12-25 | — | — | US | disclosed |
| WO-2003086287-A2 | COMPOUNDS AND METHODS FOR INDUCING APOPTOSIS IN PROLIFERATING CELLS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236294-A1 | Compounds and methods for inducing apoptosis in proliferating cells | MCL1, BRDT, BAD | PTGES 893/4885PTGS2 392/4885PTGS1 298/4885 |
| US-20260069587-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES | GCDH, PLIN3, PRPH | PTGES 698/4885PTGS2 1271/4885PTGS1 2093/4885 |
| US-20250332262-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES | PDE3A, PDE3B, PDE5A | PTGES 192/4885PTGS2 304/4885PTGS1 188/4885 |
| US-20090062227-A1 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS BY STIMULATING ER STRESS | ATP2A1, ATP2A2, ATP2A3 | PTGES 84/4885PTGS2 13/4885PTGS1 23/4885 |
| US-20230405125-A1 | TREATMENT OF RECURRENT GIOBLASTOMA WITH PERILLYL ALCOHOL | IDH3A, IDH1, IDH3B | PTGES 2753/4885PTGS2 1517/4885PTGS1 1644/4885 |
| US-20060142368-A1 | Compounds and methods for inducing apoptosis in proliferating cells | MCL1, BRDT, BAD | PTGES 877/4885PTGS2 370/4885PTGS1 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.