SCHEMBL2228686

SCHEMBL2228686

CCC(=O)Oc1c(-n2nc3ccc(Cl)cc3n2)cccc1C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.36
TRPV1 Q8NER1 5/20 0.35
TP53 P04637 4/20 0.35
ALDH1A1 P00352 6/20 0.34
HPGD P15428 4/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
HSD17B10 Q99714 1/20 0.34
PKM P14618 1/20 0.34
KDM4E B2RXH2 4/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33
NLRP3 Q96P20 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
LMNA P02545 1/20 0.32
MITF O75030 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6295772 0.88 EPHX2 (0.36) ALDH1A1SMN1; SMN2MAPK1TDP1
SCHEMBL574766 0.88 NPC1 (0.39) MAPTALDH1A1HPGDNPC1RAB9A
SCHEMBL6571748 0.81 MAPT (0.32) MAPTTP53ALDH1A1KDM4EGAA
SCHEMBL6295771 0.81 CNR1 (0.34) MAPT
Propionic Acid SCHEMBL2228683 0.81 NPC1 (0.36) MAPTTP53ALDH1A1HPGDNPC1
SCHEMBL6571752 0.80 PKM (0.31) ALDH1A1NPC1RAB9ASMN1; SMN2PKM
SCHEMBL8376178 0.80 NR1H4 (0.36) MAPTTP53ALDH1A1HPGDNPC1
SCHEMBL6571742 0.79 MEN1 (0.33) MAPTTP53ALDH1A1HPGDNPC1
SCHEMBL6295770 0.78 EPHX2 (0.38) MAPTTP53ALDH1A1HPGDHSD17B10
SCHEMBL30426108 0.77 CA2 (0.42) MAPTTP53ALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5980851-A Transparent electrically conductive plate NIPPON OIL, CO., LTD. (JP) 1999-11-09 US claimed
US-5770314-A Transparent electrically conductive plate NIPPON OIL CO., LTD. (JP) 1998-06-23 US claimed
EP-0545442-B1 Microcapsule containing ultraviolet absorber and heat sensitive recording material using the same NEW OJI PAPER CO LTD (JP) 1995-04-05 EP claimed
EP-1696053-B1 NANO-ARRAY ELECTRODE MANUFACTURING METHOD AND PHOTOELECTRIC CONVERTER USING SAME NIPPON OIL CORP (JP) 2012-12-05 EP disclosed
US-7977131-B2 Method for manufacturing nano-array electrode and photoelectric conversion device using same NIPPON OIL CORPORATION (JP) 2011-07-12 US disclosed
EP-1494308-B1 PHOTOELECTRIC CONVERSION ELEMENT NIPPON OIL CORP (JP) 2010-09-01 EP disclosed
US-20100132772-A1 METHOD FOR MANUFACTURING NANO-ARRAY ELECTRODE AND PHOTOELECTRIC CONVERSION DEVICE USING SAME NIPPON OIL CORPORATION (JP) 2010-06-03 US disclosed
EP-0913446-B1 ULTRAVIOLET ABSORBING MATERIAL AND ULTRAVIOLET ABSORBING PLATE NIPPON MITSUBISHI OIL CORP (JP) 2008-08-20 EP disclosed
US-20060234505-A1 METHOD FOR MANUFACTURING NANO-ARRAY ELECTRODE AND PHOTOELECTRIC CONVERSION DEVICE USING SAME NIPPON OIL CORPORATION (JP) 2006-10-19 US disclosed
EP-1696053-A1 NANO-ARRAY ELECTRODE MANUFACTURING METHOD AND PHOTOELECTRIC CONVERTER USING SAME Nippon Oil Corporation (JP) 2006-08-30 EP disclosed
US-20050263183-A1 Photoelectric converting device NIPPON OIL CORPORATION 2005-12-01 US disclosed
EP-0732361-B1 Ultraviolet absorber and coating material NIPPON OIL CO LTD (JP) 1999-10-06 EP disclosed
EP-0913446-A1 ULTRAVIOLET ABSORBING MATERIAL AND ULTRAVIOLET ABSORBING PLATE Nippon Oil Co., Ltd. (JP) 1999-05-06 EP disclosed
US-5859722-A Electrochromic device NIPPOM OIL CO., LTD (JP) 1999-01-12 US disclosed
EP-0855615-A2 Electrochromic device NIPPON OIL Co. Ltd. (JP) 1998-07-29 EP disclosed
US-5770314-A Transparent electrically conductive plate NIPPON OIL CO., LTD. (JP) 1998-06-23 US disclosed
US-5627227-A Ultraviolet absorber and coating material NIPPON OIL CO., LTD. (JP) 1997-05-06 US disclosed
EP-0752612-A1 Electrochromic device NIPPON OIL CO., LTD. (JP) 1997-01-08 EP disclosed
EP-0736794-A2 Transparent electrically conductive plate NIPPON OIL CO., LTD. (JP) 1996-10-09 EP disclosed
EP-0732361-A1 Ultraviolet absorber and coating material NIPPON OIL CO., LTD. (JP) 1996-09-18 EP disclosed