SCHEMBL6571748

SCHEMBL6571748

C=CCc1cc(-n2nc3ccc(Cl)cc3n2)c(OC(=O)CC)c(C(C)(C)C)c1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 3/20 0.31
GAA P10253 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
TP53 P04637 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6295771 0.84 CNR1 (0.34) MAPT
SCHEMBL2228686 0.81 MAPT (0.36) MAPTKDM4EALDH1A1GAATP53
SCHEMBL8069924 0.81 NPC1 (0.36) MAPTKDM4EMEN1KMT2ANPSR1
SCHEMBL10580258 0.77 ALDH1A1 (0.35) MAPTKDM4EALDH1A1RXFP1TP53
SCHEMBL31025700 0.75 MEN1 (0.35) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL8376178 0.75 NR1H4 (0.36) MAPTKDM4ENPSR1ALDH1A1GAA
SCHEMBL9879793 0.74 VCAM1 (0.36) KMT2A
SCHEMBL10501802 0.73 ALDH1A1 (0.37) MAPTKDM4EMEN1KMT2ANPSR1
SCHEMBL6571742 0.73 MEN1 (0.33) MAPTKDM4EMEN1KMT2ANPSR1
SCHEMBL10503537 0.73 NPC1 (0.46) MAPTKDM4ENPSR1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0752612-B1 Electrochromic device NIPPON MITSUBISHI OIL CORP (JP) 2004-04-21 EP disclosed
US-5859722-A Electrochromic device NIPPOM OIL CO., LTD (JP) 1999-01-12 US disclosed
EP-0752612-A1 Electrochromic device NIPPON OIL CO., LTD. (JP) 1997-01-08 EP disclosed