SCHEMBL574766

SCHEMBL574766

CCC(=O)Oc1c(-n2nc3ccccc3n2)cccc1C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
HPGD P15428 2/20 0.38
POLB P06746 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
NLRP3 Q96P20 1/20 0.37
BCHE P06276 1/20 0.36
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
KMT2A Q03164 1/20 0.35
RELA Q04206 1/20 0.35
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2228686 0.88 MAPT (0.36) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL2230003 0.86 NPC1 (0.50) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29213720 0.80 KCNMA1 (0.44) SMN1; SMN2KDM4EPOLBNPSR1KMT2A
SCHEMBL3106511 0.79 NLRP3 (0.44) ALDH1A1SMN1; SMN2KDM4ENLRP3KMT2A
SCHEMBL8580605 0.77 NPC1 (0.43) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29791013 0.77 NPC1 (0.43) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
Propionic Acid SCHEMBL5630265 0.77 CA2 (0.41) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL15548141 0.77 KDM4E (0.41) ALDH1A1KDM4ETDP1NLRP3BCHE
SCHEMBL6295772 0.76 EPHX2 (0.36) ALDH1A1SMN1; SMN2TDP1KMT2A
SCHEMBL30007486 0.75 KDM4E (0.38) ALDH1A1SMN1; SMN2KDM4ETDP1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325210-A Ageing-resistant rubber material for sealing ring and preparation method thereof 扬州赛普润橡塑有限公司 2024-07-12 CN claimed
CN-118325210-A Ageing-resistant rubber material for sealing ring and preparation method thereof 扬州赛普润橡塑有限公司 2024-07-12 CN disclosed
EP-2601257-A1 STABILIZED PHOTOACTIVE COMPOSITION AND USE THEREOF ENI S.p.A. (IT) 2013-06-12 EP disclosed
WO-2012017046-A1 STABILIZED PHOTOACTIVE COMPOSITION AND USE THEREOF ENI S.P.A. (IT) 2012-02-09 WO disclosed
EP-0342974-B1 Bisurea light stabilizer for organic polymers DU PONT (US) 1994-03-02 EP disclosed
US-5166234-A Ultraviolet radiation resistance; spandex E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-24 US disclosed
US-5081258-A Spandex\ E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-14 US disclosed