Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228696 | 0.84 | MMP2 (0.48) | MMP2MMP9GRIN2B | |
| SCHEMBL2363729 | 0.82 | MGLL (0.44) | MMP2MMP9MGLLUSP30 | |
| SCHEMBL2228670 | 0.82 | MMP2 (0.45) | MMP2MMP9GRIN2B | |
| SCHEMBL2228689 | 0.82 | MMP2 (0.43) | MMP2MMP9GRIN2BMGLL | |
| SCHEMBL2228470 | 0.82 | MMP2 (0.47) | MMP2MMP9GRIN2B | |
| SCHEMBL2228990 | 0.80 | MMP2 (0.46) | MMP2MMP9GRIN2B | |
| SCHEMBL2229023 | 0.80 | MMP2 (0.45) | MMP2MMP9GRIN2BMGLL | |
| SCHEMBL2362512 | 0.80 | MMP2 (0.43) | MMP2MMP9GRIN2B | |
| SCHEMBL2227253 | 0.79 | MMP2 (0.43) | MMP2MMP9GRIN2B | |
| SCHEMBL2229360 | 0.79 | MMP2 (0.43) | MMP2MMP9GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |