Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228484 | 0.76 | MAPT (0.44) | ALDH1A1HPGDALOX15NPSR1KDM4E | |
| SCHEMBL12517668 | 0.73 | ALDH1A1 (0.59) | ALDH1A1HPGDALOX15NPSR1KDM4E | |
| SCHEMBL13651125 | 0.64 | ALDH1A1 (0.55) | ALDH1A1HPGDALOX15KDM4ERXFP1 | |
| SCHEMBL20673899 | 0.63 | PDE10A (0.41) | KDM4EVCPADORA2A | |
| SCHEMBL21958603 | 0.63 | PDE10A (0.39) | ALDH1A1KDM4EL3MBTL1GAACYP2D6 | |
| SCHEMBL2219841 | 0.62 | KMT2A (0.48) | ALDH1A1HPGDKDM4ETHRBTP53 | |
| SCHEMBL13651130 | 0.62 | DDX3X (0.49) | ALDH1A1HPGDALOX15NPSR1KDM4E | |
| SCHEMBL23937735 | 0.61 | HTR4 (0.50) | CYP2D6 | |
| SCHEMBL15887206 | 0.61 | HPGD (0.60) | ALDH1A1HPGDALOX15NPSR1KDM4E | |
| SCHEMBL14552917 | 0.60 | ALDH1A1 (0.63) | ALDH1A1HPGDALOX15NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | disclosed |