Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HEXA | P06865 | 1/20 | 0.38 |
| ▸ | HEXB | P07686 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605971 | 0.68 | TAAR1 (0.49) | TAAR1TSHRADCY10HTR6DHFR | |
| SCHEMBL27286635 | 0.67 | DHFR (0.62) | DHFR | |
| SCHEMBL27230096 | 0.67 | HEXA (0.53) | HEXAHEXBADRA2ADHFRALDH1A1 | |
| SCHEMBL2030841 | 0.67 | TAAR1 (0.71) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL4230867 | 0.66 | TAAR1 (0.54) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL29176773 | 0.66 | HEXA (0.36) | HEXAHEXBPTGS2 | |
| SCHEMBL22289829 | 0.66 | MEN1 (0.37) | HEXAHEXBDHFRADORA2AADORA1 | |
| SCHEMBL5806103 | 0.63 | TAAR1 (0.55) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL14869658 | 0.63 | HTR6 (0.62) | TAAR1TSHRHTR6HTR2CHTR7 | |
| SCHEMBL29167134 | 0.62 | HTR6 (0.64) | TAAR1TSHRADCY10HTR6DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917914-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2021-12-08 | — | — | EP | claimed |
| WO-2020160202-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2020-08-06 | — | — | WO | claimed |
| EP-3917914-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020160202-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2020-08-06 | — | — | WO | disclosed |