Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.32 |
| ▸ | HEXB | P07686 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28250902 | 0.77 | KMT2A (0.36) | KMT2ADHFRKDM4EGAACCNE2 | |
| SCHEMBL22290011 | 0.69 | DHFR (0.33) | DHFR | |
| SCHEMBL29490052 | 0.68 | DCPS (0.44) | DHFRADORA2A | |
| SCHEMBL2030838 | 0.66 | ALOX5 (0.47) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL22289828 | 0.66 | TAAR1 (0.40) | DHFRKDM4EALDH1A1LMNAGLA | |
| SCHEMBL1309059 | 0.62 | — | — | |
| SCHEMBL12310754 | 0.62 | ALOX5 (0.41) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL16746829 | 0.61 | ALOX5 (0.36) | MEN1KMT2AKDM4EALDH1A1CCNE2 | |
| SCHEMBL3563625 | 0.60 | HSP90AA1 (0.41) | DHFRKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL12260273 | 0.59 | ALOX5 (0.39) | MEN1KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917914-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2021-12-08 | — | — | EP | claimed |
| WO-2020160202-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2020-08-06 | — | — | WO | claimed |
| EP-3917914-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020160202-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2020-08-06 | — | — | WO | disclosed |