Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 4/20 | 0.44 |
| ▸ | DHFR | P00374 | 10/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25247021 | 0.77 | DHFR (0.49) | DCPSDHFRKCNH2 | |
| SCHEMBL23500489 | 0.69 | DHFR (0.64) | DCPSDHFRKCNH2 | |
| SCHEMBL27446978 | 0.69 | DHFR (0.55) | DCPSDHFRKCNH2ADORA2A | |
| SCHEMBL22289829 | 0.68 | MEN1 (0.37) | DHFRADORA2A | |
| SCHEMBL1154364 | 0.67 | DCPS (0.64) | DCPSDHFRKCNH2 | |
| SCHEMBL1153306 | 0.66 | DHFR (0.58) | DCPSDHFRKCNH2 | |
| SCHEMBL2030838 | 0.66 | ALOX5 (0.47) | — | |
| SCHEMBL27286635 | 0.66 | DHFR (0.62) | DCPSDHFR | |
| SCHEMBL29740318 | 0.66 | DCPS (0.61) | DCPSDHFRKCNH2 | |
| SCHEMBL3340224 | 0.66 | DCPS (0.61) | DCPSDHFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11318137-B2 | Quinazoline compounds as modulators of Ras signaling | VANDERBILT UNIVERSITY (US) | 2022-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11318137-B2 | Quinazoline compounds as modulators of Ras signaling | NRAS, KRAS, MAVS | DCPS 3927/4885DHFR 3944/4885KCNH2 2988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.