Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 10/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23731954 | 0.87 | SMYD3 (0.32) | SMYD3 | |
| SCHEMBL16535011 | 0.85 | MEN1 (0.42) | USP30SMYD3 | |
| SCHEMBL4733881 | 0.82 | GABRG2 (0.35) | GABRG2GABRB3GABRA1GABRA2GABRA3 | |
| SCHEMBL23705567 | 0.78 | PLA2G4A (0.37) | USP30 | |
| SCHEMBL22290701 | 0.78 | GABRG2 (0.34) | GABRG2GABRB3GABRA1GABRA2GABRA3 | |
| SCHEMBL4735220 | 0.76 | RBP4 (0.51) | HPGDSUSP30 | |
| SCHEMBL19356955 | 0.74 | GABRG2 (0.38) | GABRG2GABRB3GABRA1GABRA2GABRA3 | |
| SCHEMBL22981449 | 0.74 | GABRG2 (0.37) | GABRG2GABRB3GABRA1GABRA2GABRA3 | |
| SCHEMBL22290481 | 0.73 | CA12 (0.35) | GABRG2GABRB3GABRA1GABRA2GABRA3 | |
| Trifluoroacetic Acid SCHEMBL4738880 | 0.71 | RBP4 (0.47) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917527-B1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC (US) | 2025-04-23 | — | — | EP | disclosed |
| US-20230121497-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-04-20 | — | — | US | disclosed |
| US-20230079819-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-03-16 | — | — | US | disclosed |
| EP-4096668-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| EP-3917527-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2021-12-08 | — | — | EP | disclosed |
| CN-113645971-A | Compound and use thereof | 福宏治疗公司 | 2021-11-12 | — | — | CN | disclosed |
| WO-2021155264-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| WO-2021155264-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230079819-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | GABRG2 767/4885GABRB3 377/4885GABRA1 749/4885 |
| US-20230121497-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | GABRG2 767/4885GABRB3 377/4885GABRA1 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.