Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 12/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 11/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 11/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290404 | 0.82 | GABRG2 (0.34) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL4738757 | 0.80 | PLA2G4A (0.40) | SMYD3 | |
| SCHEMBL4735031 | 0.80 | SCD (0.32) | — | |
| SCHEMBL4735220 | 0.79 | RBP4 (0.51) | HPGDS | |
| SCHEMBL19356955 | 0.77 | GABRG2 (0.38) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| Trifluoroacetic Acid SCHEMBL4735033 | 0.74 | PLA2G4A (0.36) | SMYD3 | |
| Trifluoroacetic Acid SCHEMBL4738880 | 0.74 | RBP4 (0.47) | — | |
| SCHEMBL31332879 | 0.72 | MEN1 (0.42) | SMYD3NOTUM | |
| SCHEMBL22290701 | 0.71 | GABRG2 (0.34) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL23731954 | 0.70 | SMYD3 (0.32) | SMYD3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |