SCHEMBL4611932

SCHEMBL4611932

CC(=O)C(O)C(O)OP(=O)(O)O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGD P52209 3/20 0.33
PTPN1 P18031 1/20 0.33
SMPD1 P17405 3/20 0.32
LAP3 P28838 2/20 0.32
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43278 0.75 SMPD1 (0.34) PGDPTPN1SMPD1PGK1PGK2
SCHEMBL2229219 0.74 PTPN1 (0.39) PGDPTPN1SMPD1PGK1PGK2
Phosphoric Acid SCHEMBL2148162 0.73 SMPD1 (0.33) PGDPTPN1SMPD1PGK1PGK2
SCHEMBL28301016 0.72 SMPD1 (0.35) PTPN1SMPD1LAP3PGK1PGK2
SCHEMBL31316283 0.72 LAP3 (0.36) PTPN1SMPD1LAP3PGK1PGK2
SCHEMBL2160083 0.71 PGD (0.31) PGD
SCHEMBL8060226 0.71 FDPS (0.37) PGDPTPN1SMPD1PGK1PGK2
SCHEMBL183389 0.70 SMPD1 (0.34) SMPD1PGK1PGK2
SCHEMBL28302194 0.70 SMPD1 (0.34) PTPN1SMPD1LAP3
SCHEMBL4825537 0.68 CA4 (0.35) SMPD1LAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590446-B2 Microorganism for simultaneously producing L-amino acid and riboflavin, and method for producing L-amino acid and riboflavin using same CJ CHEILJEDANG CORPORATION (KR) 2020-03-17 US disclosed
US-10245262-B2 Immunological reagents and uses therefor THE UNIVERSITY OF QUEENSLAND (AU) 2019-04-02 US disclosed
US-20170209442-A1 IMMUNOLOGICAL REAGENTS AND USES THEREFOR MONASH UNIVERSITY (AU) 2017-07-27 US disclosed
WO-2015149130-A9 IMMUNOLOGICAL REAGENTS AND USES THEREFOR THE UNIVERSITY OF QUEENSLAND (AU) 2015-11-19 WO disclosed
WO-2015149130-A1 IMMUNOLOGICAL REAGENTS AND USES THEREFOR THE UNIVERSITY OF QUEENSLAND (AU) 2015-10-08 WO disclosed
US-20140356518-A1 MICROORGANISM FOR SIMULTANEOUSLY PRODUCING L-AMINO ACID AND RIBOFLAVIN, AND METHOD FOR PRODUCING L-AMINO ACID AND RIBOFLAVIN USING SAME CJ CHEILJEDANG CORPORATION (KR) 2014-12-04 US disclosed
EP-2787082-A1 MICROORGANISM FOR SIMULTANEOUSLY PRODUCING L-AMINO ACID AND RIBOFLAVIN, AND METHOD FOR PRODUCING L-AMINO ACID AND RIBOFLAVIN USING SAME Cj Cheiljedang Corporation (KR) 2014-10-08 EP disclosed
EP-2540831-A2 Transgenic plants with enhanced agronomic traits Monsanto Technology, LLC (US) 2013-01-02 EP disclosed
EP-1332207-B1 TRANSFORMATION SYSTEMS FOR FLAVINOGENIC YEAST ARCHER DANIELS MIDLAND CO (US) 2008-10-29 EP disclosed
EP-0405370-B2 Riboflavinoverproducing strains of bacteria DSM IP ASSETS BV (NL) 2007-12-19 EP disclosed
US-6420135-B1 POLYNUCLEOTIDE AND POLYPEPTIDE SEQUENCE INFORMATION STORED ON COMPUTER READABLE MEDIA HUMAN GENOME SCIENCES, INC. 2002-07-16 US disclosed
WO-2002006448-A2 TRANSFORMATION SYSTEMS FOR FLAVINOGENIC YEAST ARCHER-DANIELS-MIDLAND COMPANY (US) 2002-01-24 WO disclosed
US-6322995-B1 RECOMBINANT GRAM POSITIVE BACTERIUM USED FOR PRODUCING RIBOFLAVIN F. HOFFMANN-LA ROCHE AG (CH) 2001-11-27 US disclosed
EP-1051504-A2 RIBOFLAVIN BIOSYNTHESIS GENES FROM PLANTS AND USES THEREOF Novartis AG (CH) 2000-11-15 EP disclosed
EP-0405370-B1 Riboflavinoverproducing strains of bacteria HOFFMANN LA ROCHE (CH) 2000-08-30 EP disclosed
EP-1001026-A2 Riboflavinoverproducing strains of bacteria F. Hoffmann-La Roche AG (CH) 2000-05-17 EP disclosed
WO-1999038986-A2 RIBOFLAVIN BIOSYNTHESIS GENES FROM PLANTS AND USES THEREOF NOVARTIS AG (CH) 1999-08-05 WO disclosed
US-5925538-A CULTURING RECOMBINANT BACTERIUM HAVING EXOGENOUS NUCLEIC ACID SEQUENCE CODING FOR PROMOTER AND OPEN READING FRAME 3 STRUCTURAL GENE SIMILAR TO A BACILLUS SUBTILIS RIBOFLAVIN OPERON GENE, RECOVERING AT LEAST 10 GRAMS PER LITER ROCHE VITAMINS INC. (US) 1999-07-20 US disclosed
US-5837528-A NUCLEOTIDE SEQUENCE OF RIB OPERON AND ITS OPEN READING FRAMES; GENETIC ENGINEERING HOFFMANN LA ROCHE, INC. (US) 1998-11-17 US disclosed
EP-0405370-A1 Riboflavinoverproducing strains of bacteria F. HOFFMANN-LA ROCHE AG (CH) 1991-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10245262-B2 Immunological reagents and uses therefor CD81, MRGPRX2, MRGPRX1 PGD 4645/4885PTPN1 1432/4885SMPD1 1362/4885
US-20170209442-A1 IMMUNOLOGICAL REAGENTS AND USES THEREFOR CD81, MRGPRX2, MRGPRX1 PGD 4645/4885PTPN1 1432/4885SMPD1 1362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.