Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.33 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CMKLR1 | Q99788 | 3/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18974930 | 0.84 | CMKLR1 (0.37) | EPHX1ALDH1A1HPGDMEN1THRB | |
| SCHEMBL22293276 | 0.83 | EPHX1 (0.36) | EPHX1ALDH1A1HPGDMEN1THRB | |
| SCHEMBL18974929 | 0.82 | CMKLR1 (0.45) | EPHX1ALDH1A1HPGDMEN1THRB | |
| SCHEMBL18974937 | 0.81 | CMKLR1 (0.46) | EPHX1ALDH1A1HPGDMEN1THRB | |
| SCHEMBL22293296 | 0.78 | SMN1; SMN2 (0.36) | EPHX1ALDH1A1HPGDMEN1THRB | |
| SCHEMBL22293231 | 0.77 | TRPM8 (0.37) | EPHX1ALDH1A1KDM4EPOLBPPARA | |
| SCHEMBL18974940 | 0.75 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTSMN1; SMN2CMKLR1 | |
| SCHEMBL18974555 | 0.74 | TAS2R14 (0.35) | CNR2PPARGPPARA | |
| SCHEMBL18975167 | 0.72 | GAA (0.37) | ALDH1A1HPGDMEN1THRBKMT2A | |
| SCHEMBL18974569 | 0.72 | CMKLR1 (0.38) | NPC1RAB9ACMKLR1CNR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388425-B1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2020-08-05 | — | — | EP | disclosed |