Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975170 | 0.83 | CMKLR1 (0.42) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL18975177 | 0.83 | CMKLR1 (0.43) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL22293306 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL18975167 | 0.82 | GAA (0.37) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL22293231 | 0.79 | TRPM8 (0.37) | ALDH1A1KDM4EPOLBEPHX1PSEN1 | |
| SCHEMBL22293235 | 0.78 | EPHX1 (0.33) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL18975107 | 0.76 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL18975178 | 0.76 | PSEN1 (0.37) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL22293302 | 0.75 | NR1D1 (0.37) | SMN1; SMN2ALDH1A1HTTCNR2NPC1 | |
| SCHEMBL22292922 | 0.75 | SLC6A4 (0.37) | MEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388425-B1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2020-08-05 | — | — | EP | disclosed |