Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22292917 | 0.90 | ALDH1A1 (0.36) | KDM4EALDH1A1HTR2BACHEPPARD | |
| SCHEMBL22293305 | 0.90 | CNR1 (0.36) | KDM4EALDH1A1ACHEBCHEPPARD | |
| SCHEMBL22293302 | 0.88 | NR1D1 (0.37) | ALDH1A1SLC6A4 | |
| SCHEMBL22293291 | 0.88 | KDM4E (0.37) | KDM4EALDH1A1HTR2BOPRM1OPRD1 | |
| SCHEMBL22293272 | 0.81 | ALDH1A1 (0.39) | KDM4EALDH1A1HTR2BSLC6A4 | |
| SCHEMBL22293282 | 0.79 | HPGD (0.35) | BCHE | |
| SCHEMBL22293004 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1HTR2B | |
| SCHEMBL22292961 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1HTR2BPPARDSIGMAR1 | |
| SCHEMBL18975162 | 0.76 | LPAR1 (0.40) | ALDH1A1HTR2BACHESLC6A4BCHE | |
| SCHEMBL18974645 | 0.75 | LPAR1 (0.40) | ALDH1A1HTR2BACHESLC6A4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388425-B1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2020-08-05 | — | — | EP | disclosed |