Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22293268 | 0.88 | KDM4E (0.36) | KDM4EALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL22293272 | 0.82 | ALDH1A1 (0.39) | KDM4EALDH1A1HTR2BG6PC1USP2 | |
| SCHEMBL22293305 | 0.80 | CNR1 (0.36) | KDM4EALDH1A1NPC1RAB9ACNR1 | |
| SCHEMBL22292917 | 0.78 | ALDH1A1 (0.36) | KDM4EALDH1A1HTR2BNPC1RAB9A | |
| SCHEMBL22293302 | 0.78 | NR1D1 (0.37) | ALDH1A1ATMNPC1RAB9AMAPK1 | |
| SCHEMBL22293004 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1HTR2BG6PC1RAB9A | |
| SCHEMBL22293189 | 0.76 | CYP19A1 (0.33) | OPRM1OPRD1OPRK1CNR2 | |
| SCHEMBL22292920 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1 | |
| SCHEMBL18974921 | 0.75 | CMKLR1 (0.41) | ALDH1A1ATMHDAC1HDAC6MAPK1 | |
| SCHEMBL22293027 | 0.74 | ALDH1A1 (0.42) | KDM4EALDH1A1HTR2BHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388425-B1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2020-08-05 | — | — | EP | disclosed |