Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 3/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22293254 | 0.84 | G6PC1 (0.39) | ALDH1A1G6PC1HSD17B10USP2HPGD | |
| SCHEMBL22293291 | 0.82 | KDM4E (0.37) | ALDH1A1KDM4EHTR2BG6PC1HSD17B10 | |
| SCHEMBL22293268 | 0.81 | KDM4E (0.36) | ALDH1A1KDM4EHTR2BSLC6A4 | |
| SCHEMBL22293027 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KDM4EHTR2BHSD17B10L3MBTL1 | |
| SCHEMBL22293004 | 0.76 | KDM4E (0.41) | ALDH1A1KDM4EHTR2BG6PC1L3MBTL1 | |
| SCHEMBL18974924 | 0.75 | LPAR1 (0.42) | KDM4EHSD17B10USP2HPGDMAPK1 | |
| SCHEMBL22292917 | 0.74 | ALDH1A1 (0.36) | ALDH1A1KDM4EHTR2BMAPK1CPB1 | |
| SCHEMBL18974925 | 0.74 | MAPK1 (0.42) | ALDH1A1HSD17B10USP2HPGDMAPK1 | |
| SCHEMBL22292920 | 0.73 | KDM4E (0.44) | ALDH1A1KDM4EMAPT | |
| SCHEMBL22293098 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4EHTR2BMAPK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388425-B1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2020-08-05 | — | — | EP | disclosed |