Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22293305 | 0.82 | CNR1 (0.36) | BCHE | |
| SCHEMBL22293302 | 0.80 | NR1D1 (0.37) | — | |
| SCHEMBL22293268 | 0.79 | KDM4E (0.36) | BCHE | |
| SCHEMBL22292917 | 0.71 | ALDH1A1 (0.36) | CHRM2CHRM1CHRM3 | |
| SCHEMBL18975172 | 0.70 | TRPM8 (0.39) | AVPR1B | |
| SCHEMBL22293291 | 0.70 | KDM4E (0.37) | HPGD | |
| SCHEMBL18975180 | 0.68 | CXCR3 (0.39) | AVPR1B | |
| SCHEMBL18974573 | 0.67 | CXCR3 (0.38) | AVPR1B | |
| SCHEMBL22292930 | 0.67 | PTGDR2 (0.37) | — | |
| SCHEMBL22293080 | 0.66 | BCHE (0.35) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388425-B1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2020-08-05 | — | — | EP | disclosed |