Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22293272 | 0.84 | ALDH1A1 (0.39) | G6PC1USP2HPGDHSD17B10MAPK1 | |
| SCHEMBL18974925 | 0.77 | MAPK1 (0.42) | USP2HPGDHSD17B10MAPK1AGER | |
| SCHEMBL18974924 | 0.76 | LPAR1 (0.42) | USP2HPGDHSD17B10MAPK1AGER | |
| SCHEMBL9057205 | 0.74 | G6PC1 (0.39) | G6PC1USP2HPGDHSD17B10MAPK1 | |
| SCHEMBL10891206 | 0.72 | G6PC1 (0.50) | G6PC1USP2HPGDHSD17B10MAPK1 | |
| SCHEMBL4476467 | 0.72 | G6PC1 (0.54) | G6PC1USP2HPGDHSD17B10MAPK1 | |
| SCHEMBL9057640 | 0.72 | CYP2C19 (0.53) | G6PC1USP2HPGDHSD17B10MAPK1 | |
| SCHEMBL8794535 | 0.71 | CRHR1 (0.43) | KMT2A | |
| SCHEMBL11693064 | 0.70 | S1PR1 (0.48) | G6PC1USP2HPGDHSD17B10SLC6A2 | |
| SCHEMBL6456177 | 0.69 | SLC6A2 (0.42) | G6PC1USP2HPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388425-B1 | AMINOAZOLE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2020-08-05 | — | — | EP | disclosed |