SCHEMBL222935

SCHEMBL222935

O=[N+]([O-])c1cc(I)cc(I)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.56
MEN1 O00255 3/20 0.56
HTT P42858 3/20 0.56
KMT2A Q03164 3/20 0.56
CYP19A1 P11511 1/20 0.55
TSHR P16473 2/20 0.50
ALDH1A1 P00352 5/20 0.48
VCAM1 P19320 1/20 0.44
CYP3A4 P08684 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
XDH P47989 1/20 0.42
POLB P06746 1/20 0.41
KDM4E B2RXH2 1/20 0.41
TTR P02766 1/20 0.41
CYP1A2 P05177 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL309438 0.94 CYP19A1 (0.62) LMNAMEN1HTTKMT2ACYP19A1
SCHEMBL30492205 0.84 LMNA (0.47) LMNAMEN1HTTKMT2ACYP19A1
SCHEMBL16955649 0.84 LMNA (0.47) LMNAMEN1HTTKMT2ACYP19A1
SCHEMBL9452187 0.84 ALDH1A1 (0.50) LMNAMEN1HTTKMT2ACYP19A1
SCHEMBL1171962 0.84 LMNA (0.47) LMNAMEN1HTTKMT2ACYP19A1
SCHEMBL29920469 0.84 LMNA (0.47) LMNAMEN1HTTKMT2ACYP19A1
SCHEMBL6651088 0.84 ALDH1A1 (0.50) LMNAMEN1HTTKMT2ACYP19A1
SCHEMBL5289451 0.84 TSHR (0.71) LMNAMEN1HTTKMT2ACYP19A1
SCHEMBL220173 0.84 LMNA (0.47) LMNAMEN1HTTKMT2ACYP19A1
SCHEMBL1689797 0.84 MEN1 (0.57) LMNAMEN1HTTKMT2ACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2115035-B1 POLYARYLENE SULFIDE RESIN WITH EXCELLENT LUMINOSITY AND PREPARATION METHOD THEREOF SK CHEMICALS CO LTD (KR) 2018-04-25 EP claimed
EP-2097470-B1 METHOD FOR PRODUCTION OF POLYARYLENE SULFIDE RESIN WITH EXCELLENT LUMINOSITY AND THE POLYARYLENE SULFIDE RESIN SK CHEMICALS CO LTD (KR) 2017-03-22 EP claimed
US-8957182-B2 Polyarylene sulfide resin with excellent luminosity and preparation method thereof SK CHEMICALS CO., LTD. (KR) 2015-02-17 US claimed
US-8883960-B2 Polyarylene sulfide resin with excellent luminosity and preparation method thereof SK CHEMICALS CO., LTD. (KR) 2014-11-11 US claimed
US-20140194592-A1 POLYARYLENE SULFIDE RESIN WITH EXCELLENT LUMINOSITY AND PREPARATION METHOD THEREOF SK CHEMICALS CO., LTD. (KR) 2014-07-10 US claimed
US-8492502-B2 Method for production of polyarylene sulfide resin with excellent luminosity and the polyarylene sulfide resin SK CHEMICALS CO., LTD. (KR) 2013-07-23 US claimed
JP-2010515781-A 2010-05-13 JP claimed
JP-2010515782-A 2010-05-13 JP claimed
US-20100105845-A1 METHOD FOR PRODUCTION OF POLYARYLENE SULFIDE RESIN WITH EXCELLENT LUMINOSITY AND THE POLYARYLENE SULFIDE RESIN SK CHEMICALS CO., LTD. (KR) 2010-04-29 US claimed
US-20100022743-A1 POLYARYLENE SULFIDE RESIN WITH EXCELLENT LUMINOSITY AND PREPARATION METHOD THEREOF SK CHEMICALS. , LTD. 2010-01-28 US claimed
EP-2115035-A1 POLYARYLENE SULFIDE RESIN WITH EXCELLENT LUMINOSITY AND PREPARATION METHOD THEREOF SK Chemicals Co., Ltd. (KR) 2009-11-11 EP claimed
EP-2097470-A1 METHOD FOR PRODUCTION OF POLYARYLENE SULFIDE RESIN WITH EXCELLENT LUMINOSITY AND THE POLYARYLENE SULFIDE RESIN SK Chemicals Co., Ltd. (KR) 2009-09-09 EP claimed
WO-2008082265-A1 POLYARYLENE SULFIDE RESIN WITH EXCELLENT LUMINOSITY AND PREPARATION METHOD THEREOF SK CHEMICALS CO., LTD. (KR) 2008-07-10 WO claimed
WO-2008082267-A1 METHOD FOR PRODUCTION OF POLYARYLENE SULFIDE RESIN WITH EXCELLENT LUMINOSITY AND THE POLYARYLENE SULFIDE RESIN SK CHEMICALS CO., LTD. (KR) 2008-07-10 WO claimed
US-12636379-B2 Microbubble-chemotherapeutic agent complex for sonodynamic therapy Sonotarg Limited (GB) 2026-05-26 US disclosed
US-12312295-B1 Chemical compound that binds to nerves while permitting detection via computed tomography or x-ray MCCARTHY JAMES EDWARD (US) 2025-05-27 US disclosed
CN-117088916-A Fluorine-containing probe for detecting trace amount of substance to be detected, and preparation and application thereof 中国科学院上海有机化学研究所 2023-11-21 CN disclosed
US-4792600-A FROM DIIODOAROMATIC COMPOUND AND SULFUR EASTMAN KODAK COMPANY (US) 1988-12-20 US disclosed
US-4786713-A Copoly(arylene sulfidex-disulfide) EASTMAN KODAK COMPANY (US) 1988-11-22 US disclosed
US-4011265-A 3,3\"-Diamino- or 3,3\"-dimethoxy-octanitro-m-terphenyl THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636379-B2 Microbubble-chemotherapeutic agent complex for sonodynamic therapy SON, BID, BCL2 LMNA 1973/4885MEN1 2056/4885HTT 1297/4885
US-12312295-B1 Chemical compound that binds to nerves while permitting detection via computed tomography or x-ray CNR1, HCAR3, HRH3 LMNA 1880/4885MEN1 1114/4885HTT 1695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.