Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436027 | 0.86 | GRM2 (0.47) | CA1CA2F10HTR2AGRM2 | |
| SCHEMBL17493553 | 0.79 | FFAR1 (0.55) | FFAR4FFAR1 | |
| SCHEMBL17423600 | 0.78 | MAOB (0.48) | TRPA1MAOBTAAR1 | |
| SCHEMBL24766983 | 0.78 | CA3 (0.44) | CA5ACA9CA5BMAOBPTPN1 | |
| SCHEMBL1133454 | 0.78 | PTGS1 (0.51) | PTPN1PPARGPTGS2PTGS1 | |
| SCHEMBL7409593 | 0.78 | ALDH1A1 (0.49) | GRM2PTPN1PPARG | |
| SCHEMBL11671157 | 0.78 | GCGR (0.46) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL1177329 | 0.76 | RXRA (0.50) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL30780084 | 0.76 | RXRA (0.50) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL418183 | 0.76 | TRPA1 (0.48) | TRPA1MAOBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209491-A1 | ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS | Innovative Molecules GmbH (DE) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022090409-A1 | DEUTERATED AMINOTHIAZOLE COMPOUNDS AS ANTIVIRAL COMPOUNDS | INNOVATIVE MOLECULES GMBH (DE) | 2022-05-05 | — | — | WO | disclosed |
| EP-3440063-B1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | INNOVATIVE MOLECULES GMBH (DE) | 2020-08-05 | — | — | EP | disclosed |