Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.37 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912308 | 0.94 | PTPRC (0.44) | ALDH1A1TDP1KMT2AMEN1NSD2 | |
| SCHEMBL181454 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TDP1KMT2AMEN1NSD2 | |
| SCHEMBL2752345 | 0.86 | CYP2A6 (0.54) | ALDH1A1TDP1NSD2BCHEDAO | |
| SCHEMBL10949160 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TDP1KMT2AMEN1AKR1B1 | |
| SCHEMBL2844949 | 0.79 | NSD2 (0.39) | ALDH1A1TDP1KMT2AMEN1NSD2 | |
| SCHEMBL154899 | 0.77 | SLC40A1 (0.44) | ALDH1A1TDP1KMT2AMEN1AKR1B1 | |
| SCHEMBL4537200 | 0.77 | PKM (0.48) | ALDH1A1TDP1KMT2AMEN1AKR1B1 | |
| SCHEMBL29907223 | 0.77 | SLC40A1 (0.44) | ALDH1A1TDP1KMT2AMEN1AKR1B1 | |
| SCHEMBL31575915 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TDP1KMT2AMEN1AKR1B1 | |
| SCHEMBL31228986 | 0.76 | DPP4 (0.35) | ALDH1A1TDP1KMT2ANSD2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519554-A2 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E.I. Du Pont De Nemours And Company (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011090705-A2 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-28 | — | — | WO | disclosed |