SCHEMBL2844949

SCHEMBL2844949

O=S(=O)(O)c1c(Cl)cccc1-c1cccc(Cl)c1S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.39
BCHE P06276 1/20 0.39
DAO P14920 1/20 0.39
CES1 P23141 1/20 0.39
ALDH1A1 P00352 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ATM Q13315 2/20 0.39
CNR1 P21554 1/20 0.38
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
DAPK1 P53355 1/20 0.37
AKR1B1 P15121 1/20 0.37
GAA P10253 1/20 0.37
MET P08581 1/20 0.37
POLB P06746 1/20 0.37
CYP2C9 P11712 1/20 0.37
IDO1 P14902 1/20 0.36
DNMT1 P26358 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440935 0.88 ALDH1A1 (0.44) ALDH1A1KMT2AMEN1TDP1ATM
SCHEMBL4630193 0.87 CYP2A6 (0.48) ALDH1A1TSHRSMN1; SMN2
Hydrochloric Acid SCHEMBL27552065 0.86 ALDH1A1 (0.42) ALDH1A1KMT2AMEN1TDP1ATM
SCHEMBL149755 0.82 TTR (0.44) ALDH1A1KMT2AMEN1TDP1ATM
SCHEMBL5728040 0.80 TSHR (0.48) ALDH1A1KMT2AMEN1TDP1ATM
SCHEMBL20855006 0.79 SLC9A1 (0.35) NSD2BCHEDAOCES1ALDH1A1
SCHEMBL2229494 0.79 ALDH1A1 (0.41) NSD2BCHEDAOCES1ALDH1A1
SCHEMBL4635992 0.78 SLC40A1 (0.43) ALDH1A1KMT2AMEN1TDP1ATM
SCHEMBL10296112 0.78 PKM (0.47) CES1ALDH1A1KMT2AMEN1TDP1
SCHEMBL6939244 0.78 TTR (0.46) ALDH1A1KMT2AMEN1TDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120251919-A1 POLYARYLENE-BASED COPOLYMER AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
EP-2489690-A1 POLYARYLENE COPOLYMER AND USES THEREOF Sumitomo Chemical Company Limited (JP) 2012-08-22 EP disclosed
US-20100129729-A1 CEOSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE,CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-05-27 US disclosed
EP-2147943-A1 CROSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE, CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL Sumitomo Chemical Company, Limited (JP) 2010-01-27 EP disclosed
US-20090253015-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2009-10-08 US disclosed