Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.32 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127239 | 0.79 | ALDH1A1 (0.48) | CES1IDO1DNMT1DNMT3LDNMT3A | |
| SCHEMBL8765394 | 0.73 | AHR (0.46) | PTGES2IDO1DNMT1DNMT3LDNMT3A | |
| SCHEMBL6949091 | 0.70 | PTGES2 (0.57) | PTGES2HSD11B1TRPV4 | |
| SCHEMBL11651755 | 0.70 | AHR (0.37) | MCOLN3PTGES2TSHRCES1IDO1 | |
| SCHEMBL196348 | 0.69 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TDP1ADORA2AACLY | |
| SCHEMBL11473674 | 0.69 | PKLR (0.39) | MCOLN3PTGES2TSHRCES1IDO1 | |
| SCHEMBL2229494 | 0.69 | ALDH1A1 (0.41) | TSHRCES1IDO1DNMT1DNMT3L | |
| SCHEMBL29519135 | 0.69 | TSHR (0.53) | MCOLN3PTGES2TSHRALDH1A1TDP1 | |
| SCHEMBL18457 | 0.69 | TSHR (0.53) | MCOLN3PTGES2TSHRALDH1A1TDP1 | |
| SCHEMBL6291104 | 0.68 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TDP1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519554-A2 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E.I. Du Pont De Nemours And Company (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011090705-A2 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-28 | — | — | WO | disclosed |